GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs7714584 | 1 | rs34156253 | chr5:150226230 | LOC134466 | chr5:150310000-150326146:- | 0.41 | 4.89 | 1.47E-6 | Crohn's disease |
| BLCA | cis | rs1109114 | 1 | rs34180939 | chr5:148618964 | AFAP1L1 | chr5:148651401-148721365:+ | 0.27 | 5.02 | 8.06E-7 | Body mass index |
| BLCA | cis | rs2243480 | 1 | rs34192067 | chr7:65887657 | CCT6P1 | chr7:65216092-65228661:+ | 0.37 | 4.98 | 9.6E-7 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs34193460 | chr7:65393110 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.47 | 1.02E-5 | Diabetic kidney disease |
| BLCA | cis | rs1577917 | 1 | rs34281561 | chr6:86701872 | SNHG5 | chr6:86386726-86388451:- | -0.52 | -9.26 | 1.43E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs13053817 | 1 | rs34305567 | chr22:29853562 | MTMR3 | chr22:30279158-30426855:+ | 0.25 | 3.93 | 0.000101 | Carotid atherosclerosis in HIV infection |
| BLCA | cis | rs13053817 | 1 | rs34305567 | chr22:29853562 | NIPSNAP1 | chr22:29950800-29977144:- | 0.3 | 4.15 | 4.1E-5 | Carotid atherosclerosis in HIV infection |
| BLCA | cis | rs34344888 | 1 | rs34344888 | chr14:23387585 | HAUS4 | chr14:23415438-23426335:- | -0.21 | -4.16 | 3.93E-5 | Educational attainment (years of education) |
| BLCA | cis | rs344081 | 1 | rs344081 | chr3:156555984 | LEKR1 | chr3:156544076-156763918:+ | -0.45 | -6.31 | 7.51E-10 | Bone mineral density |
| BLCA | cis | rs344081 | 1 | rs344088 | chr3:156561361 | LEKR1 | chr3:156544076-156763918:+ | -0.45 | -6.34 | 6.39E-10 | Bone mineral density |
| BLCA | cis | rs344081 | 1 | rs344090 | chr3:156563140 | LEKR1 | chr3:156544076-156763918:+ | -0.45 | -6.34 | 6.39E-10 | Bone mineral density |
| BLCA | cis | rs4372836 | 1 | rs34409160 | chr2:28943865 | TRMT61B | chr2:29072690-29093175:- | 0.3 | 5.29 | 2.1E-7 | Body mass index |
| BLCA | cis | rs12748152 | 1 | rs34473788 | chr1:27271519 | GPN2 | chr1:27205873-27216869:- | 0.48 | 4.1 | 5.14E-5 | HDL cholesterol;Triglycerides;LDL cholesterol |
| BLCA | cis | rs2243480 | 1 | rs34529418 | chr7:65403209 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.38 | 1.53E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs34560516 | chr7:65404092 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.47 | 1.02E-5 | Diabetic kidney disease |